Use the Variable Number of Tandem Repeats (VNTR) in DNA fingerprinting and its application biological sciences

Abstract

DNA fingerprinting is an important tool in criminal investigations. Typing of Variable Number Tandem Repeat (VNTR) is a genotyping tool that provides a numeric and simple format of data based on the repetitive sequences number. The present study uses DNA fingerprinting by amplify certain specific VNTR regions present at a particular locus of different chromosomes. The biological samples include available materials such as hair and blood present on a scene of crime, blood, buccal and along with fingernail. By amplifying he specific VNTR fragments of different DNA samples & comparing them on agarose gel electrophoresis, we obtained DNA profile of individuals, which in turn helps in criminal identification. It can also indicate whether the individuals are homozygous or heterozygous.

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