The evaluation of chip freeze-dried cancellous bone allograft of local products usage as a scaffold in completing small defects on long bone

Abstract

Background: Bone graft as a therapeutic modality for bone defects reconstruction has been widely applied. Bone autograft is the optimum comparative standard for each substitute material, but can still cause complications and limited availability. Bone allograft has long been used as a natural substitute material for bone autograft. Chip freeze-dried bone allograft is one of the allograft’s types available in various shapes and sizes, so it has the capability of filling the gaps of bone defects precisely. Purpose: This study aims to evaluate the achievement of chip freeze-dried bone allograft in completing small bone defects compared to bone autograft. Method: The researchers recapitulated the data of 10 patients with bone autograft, and chip freeze-dried bone allograft and evaluated the outcome of applying bone repair by utilizing Hammer classification on bone defects healing. The collected data were then examined statistically with the Mann-Whitney Test. Results: In the autograft group, 70% of radiological evaluations were mostly obtained from grade 2 Hammer classifications. While, in the allograft group, the highest results were obtained in grade 3 Hammer classifications, those were 40%. Statistical tests indicated that there was no significant difference in bone healing between the bone autograft and the bone allograft groups (p=0.579). Conclusion: Bone, in both groups (bone autograft and chip freeze-dried cancellous bone allograft), has the same results in terms of the healing process.

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