The effect of blood flow rates on dialysis adequacy and complications in both low and high flux membrane

Abstract

Background: Hemodialysis has been taken a major role in prolonging survive of patient with end stage renal disease (ESRD) patient. The efficacy of hemodialysis may be improved by using the difference flux dialysis membranes and blood flow rates by considering their difference complications. This study aimed to know the assess dialysis adequacy in difference blood flow rates and low and high flux membranes. Subject and materials: The research method adopted for the study was a quasi-experimental design. The researchers selected 96 hemodialysis sessions from different patients. Two difference filters were used, and BFRs have been arranged from 200ml/min, 250ml/min, and 300ml/min. The clinical signs of the patient status were assessed and monitored during dialysis. Dialysis adequacy for difference flow rates were measured based on normalized treatment ratio (Kt/V) and urea reduction rate (URR). Results: Over 58 of participants were male, with the overall mean age was (51.40±13.64). Mean Kt/V (1.31±0.43) and URR (55.09±11.68) were significantly high among female, the statistical value (P. value=0.026). The high Kt/v was seen in blood flow rate 300ml/min in low flux and high flux dialysis membranes, means was 1.33±0.35, and 1.54±0.47. Similarly, high URR was seen 300ml/min blood flow rates in high flux dialysis membrane, 64.57±6.82. Statistical difference was (p. value=0.000). The high significant Kt/V and URR were seen in dry weight patient (P. value= 0.016 and 0.021 respectively). Over (33%) of patient was developed complication during dialysis, the most frequent complications were hypotension (10%) and weakness (9%). Conclusion: dialysis adequacy is most associated with high blood flow rate with using high flux dialysis membrane. Less percentage complications have seen among dialysis patients in this study.

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