The correlation between Mmp7 and fox protein marker in oral sequamou cell carcinoma
  • Article Type: Research Article
  • Eurasian Journal of Biosciences, 2020 - Volume 14 Issue 2, pp. 4323-4329
  • Published Online: 22 Oct 2020
  • Open Access Full Text (PDF)

Abstract

In Iraqi patients with Oral Sequamou cell cancer, little is understood about the expression of Mmp7 and Fox protein. Fox ‘s positive expression was significantly associated with the location (p=0.016) and clinical appearance. Positive expression of Fox has been noted in all cases of oral sequamoucell carcinomacases that represent their essential function in inflammation, indicating that it can be used as inhibitors for head and neck malignancies to improve anti-inflammation therapies.Oral sequamou cell carcinoma mucocutaneous uncertain cause (of a disease) with an ability (to hold or do something) for harmful change is considered to be oral oral sequamous cell cancer. In Iraqi patients with Oral Sequamou cell cancer, little is understood about the expression of Mmp7 and Fox protein. The current research was aimed at assessing the expression of Mmp7 and Fox protein in the portion of Oral oral sequamou cell carcinomausing immunohistochemical teqnique in Iraq. Parts of 22 embedded formalin-fixed paraffin blocks of Oral oral sequamou cell carcinomawere immunostained to determine the expression of Mmp7 and Fox. The term Mmp7 and Fox in both oral sequamou cell carcinomacases was positive (100 percent). Fox ‘s positive expression was significantly associated with the location (p=0.016) and clinical appearance (p-value=0.003). The positive expression of Mmp7 was substantially statically associated with the location of tumors (p-value = 0.002). There was a non-significant association between Mmp7 and Fox, on the other hand (p-value=0.021). The positive expression of Mmp7 And Fox has been noted in all cases of oral sequamou cell carcinomacases that represent their essential function in inflammation, indicating that it can be used as inhibitors for head and neck malignancies to improve anti-inflammation therapies.

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