The antibacterial efficacy of the secondary metabolites extracted from (Melia azedarach L.) leaves against pathogenic microorganisms isolated from burns and gingivitis infections
Hussein J. Hussein 1 * , Ali H. Al-Marzoqi 1
1 Department of Biology, College of Science for women, University of Babylon IRAQ
* Corresponding Author
  • Article Type: Research Article
  • Eurasian Journal of Biosciences, 2020 - Volume 14 Issue 1, pp. 561-565
  • Published Online: 09 Mar 2020
  • Article Views: 54 | Article Download: 47
  • Open Access Full Text (PDF)
AMA 10th edition
In-text citation: (1), (2), (3), etc.
Reference: Hussein HJ, Al-Marzoqi AH. The antibacterial efficacy of the secondary metabolites extracted from (Melia azedarach L.) leaves against pathogenic microorganisms isolated from burns and gingivitis infections. Eurasia J Biosci. 2020;14(1), 561-565.

APA 6th edition
In-text citation: (Hussein & Al-Marzoqi, 2020)
Reference: Hussein, H. J., & Al-Marzoqi, A. H. (2020). The antibacterial efficacy of the secondary metabolites extracted from (Melia azedarach L.) leaves against pathogenic microorganisms isolated from burns and gingivitis infections. Eurasian Journal of Biosciences, 14(1), 561-565.

Chicago
In-text citation: (Hussein and Al-Marzoqi, 2020)
Reference: Hussein, Hussein J., and Ali H. Al-Marzoqi. "The antibacterial efficacy of the secondary metabolites extracted from (Melia azedarach L.) leaves against pathogenic microorganisms isolated from burns and gingivitis infections". Eurasian Journal of Biosciences 2020 14 no. 1 (2020): 561-565.

Harvard
In-text citation: (Hussein and Al-Marzoqi, 2020)
Reference: Hussein, H. J., and Al-Marzoqi, A. H. (2020). The antibacterial efficacy of the secondary metabolites extracted from (Melia azedarach L.) leaves against pathogenic microorganisms isolated from burns and gingivitis infections. Eurasian Journal of Biosciences, 14(1), pp. 561-565.

MLA
In-text citation: (Hussein and Al-Marzoqi, 2020)
Reference: Hussein, Hussein J. et al. "The antibacterial efficacy of the secondary metabolites extracted from (Melia azedarach L.) leaves against pathogenic microorganisms isolated from burns and gingivitis infections". Eurasian Journal of Biosciences, vol. 14, no. 1, 2020, pp. 561-565.

Vancouver
In-text citation: (1), (2), (3), etc.
Reference: Hussein HJ, Al-Marzoqi AH. The antibacterial efficacy of the secondary metabolites extracted from (Melia azedarach L.) leaves against pathogenic microorganisms isolated from burns and gingivitis infections. Eurasia J Biosci. 2020;14(1):561-5.

Abstract

The current investigation was accompanied to assess the antibacterial efficacy of secondary metabolites compounds, such as: phenolic, terpenoids, and alkaloids extracted from leaves of Chinaberry tree (Melia azedarach L., Family: Meliaceae) counter to pathogenic microorganisms isolated from burns and gingivitis cases. by using agar well diffusion method. The aimed of this investigation was to assess the antibacterial efficacy of Phenolic, Terpenoids, and Alkaloids extracted from leaves of Chinaberry tree (Melia azedarach L.) against some pathogenic microorganisms isolated from burns and gingivitis cases. The data collected from the study revealed that, secondary metabolites compounds, such as: phenolic, terpenoids, and alkaloids extracted from leaves of Chinaberry tree had a range of antibacterial efficacy against pathogenic microorganisms isolated from burns and gingivitis cases. Streptococcus mitis and Staphylococcus aureus were exhibited fully unaffected to phenolic and terpenoids secondary metabolites extracted from leaves of Chinaberry tree (Melia azedarach L.). Escherichia coli were fully resistant to terpenoids compounds. Staphylococcus aureus were fully resistant to alkaloids compounds. In conclusion, secondary metabolites compounds extracted leaves of Chinaberry tree (Melia azedarach L.) considered a good source for make drugs against microorganisms isolated from burns and gingivitis cases especially alkaloids compounds.

Keywords

antibacterial secondary metabolites melia azedarach pathogenic microorganisms

References

  • Al-Khafaji NJ, Al-Zubaedi RM, Al-Azawi SJ (2016) Evaluation of antibacterial effects of Melia azedarach fruit extracts against some isolated pathogenic bacteria. Veterinary Science Development 6(6080): 1-3.
  • Al-Marzoqi AH, Al-Khafaji NMS, Hussein HJ (2016) In vitro Antibacterial Activity Assessment of the crude Phenolic, Alkaloid and Terpenoid compounds extracts of Lepidium sativum L. on Human Pathogenic Bacteria. International Journal of ChemTech Research 9(4): 529-532.
  • Al-Marzoqi AH, Hussein HJ, Al-Khafaji NMS (2015) Antibacterial Activity of the Crude Phenolic, Alkaloid and Terpenoid Compounds Extracts of Lactuca serriola L. on Human Pathogenic Bacteria. Chemistry and Materials Research 7(1): 8-10.
  • Bagheri M, Yari A, Mahdipoor A (2018) Determination of lead ion by a modified carbon paste electrode based on multi-walled carbon nanotubes (MWCNTs) and poly 4-N-pyridine para styrene sulfonamide. Journal of Environmental Treatment Techniques, 6(3): 53-58.
  • Chen MS (2008) Inducible direct plant defense against insect herbivores: a review. Insect science 15(2): 101-114.
  • Cowan MM (1999) Plant products as antimicrobial agents. Clinical microbiology reviews 12(4): 564-582.
  • Harborne JB (1984) Phytochemical methods. Chapman and Hall, New York. 2nd ed: 288.
  • Harborne JB (1993) Plant secondary metabolites, J. Braz. Chem. S 14: 200-203.
  • Harborne JB, Mabray TY, Marby H (1975) Physiology and function of flavonoids. Academic Press, New York: 970.
  • Hussein HJ, Al-Khafaji NMS, Al-Mamoori AH, Al-Marzoqi AH (2018a) Evaluation of in vitro antibacterial properties of the crude Phenolic, Alkaloid and Terpenoid extracts of Cassia senna L. against Human gram-negative Pathogenic Bacteria. Plant archives 18(1): 354-356.
  • Hussein HJ, Al-Khafaji NMS, Al-Mamoori AH, Juaifer WAK, Al-Marzoqi AH, Al-Zobiady RA (2017) Antimicrobial Effect of the Crude Phenolic, Alkaloid and Terpenoid Compounds Extracts of Myrtus Communis L. against Human Gram-Negative Pathogenic Bacteria. Journal of Global Pharma Technology 9(8): 130-133.
  • Hussein HJ, Kaizal AF, Al-Khafaji NMS, Sadiq ZF, Shahad AS (2018b) Evaluation of antibacterial potential of the crude Phenolic, Alkaloid and Terpenoid extracts of Ricinus communis L. against gram-negative Pathogenic Bacteria. Journal of Global Pharma Technology 10(05): 384-388.
  • Hussein HJ, Naji SS, Al-Khafaji NMS (2018c) Antibacterial properties of the Chlorella vulgaris isolated from polluted water in Iraq. Journal of Pharmaceutical Sciences and Research 10(10): 2457-2460.
  • Hussein HJ, Sahi NM, Saad AM, Altameme HJ (2019) The Antibacterial Effect of bioactive compounds extracted from Cassia didymobotrya (Fresenius) Irwin & Barneby against some Pathogenic Bacteria. Annals of Tropical Medicine and Public Health 22(1): SPe 116.
  • Kamal AS, Hussein HJ, Tolaifeh ZA (2019) Antibacterial potential of Hibiscus sabdarifa L. against some Enterobacteriaceae: in vitro. Biochemical and cellular archives 19(2): 4291-4294.
  • Khan AV, Ahmed QU, Mir MR, Shukla I, Khan AA (2011) Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains. Asian Pacific journal of tropical biomedicine 1(6): 452-455.
  • Khan AV, Khan AA, Shukla I (2008) In Vitro Antibacterial Potential of Melia azedarach Crude Leaf Extracts Against Some Human Pathogenic Bacterial Strains. Ethnobo. Leaflets 12: 439-445.
  • Meziane MALIKA, Goumri HALIMA (2014) The antimicrobial effect of extracts of Melia azedarach on some pathogenic microorganisms. IJANS 3: 173-180.
  • Neycee MA, Nematzadeh GHA, Dehestani A, Alavi M (2012) Evaluation of antibacterial effects of chinaberry (Melia azedarach) against gram-positive and gram-negative bacteria. Int J Agric Crop Sci 4(11): 709-712.
  • Okusa PN, Stévigny C, Duez P (2009) Medicinal Plants: A Tool to Overcome Antibiotic Resistance?, in: Varela, A., & Ibañez, J.(eds). Medicinal plants: classification, biosynthesis and pharmacology. Nova Science Publishers, Incorporated: Pp, 315.
  • Perez L, Pauli M, Bazequre P (1990) Antibiotic assay by the agar well diffusion method. Journal of Actabiology 15: 113-115.
  • PONS11, N. O. V. A. L. (2017). Improvement of Maize Productivity (Zea Mays L.) by Mycorrhizal Inoculation on Ferruginous Soil in Center of Benin. International Journal, 4(3): 63-76.
  • Raffauf RF (1996) Plant alkaloids: a guide to their discovery and distribution. Haworth Press, New York, London: pp. 279.
  • Ramya S, Jepachanderamohan PJ, Kalayanasundaram M, Jayakumararaj R (2009) In vitro antibacterial prospective of crude leaf extracts of Melia azedarach Linn. against selected bacterial strains. Ethnobotanical Leaflets, 1: 32.
  • Ribereau-Gayon P (1972) Plant phenolics. Oliver and Boyd, USA: pp. 254.
  • Stipanovic RD (1983) Function and Chemistry of plant trichomes and glands in insect resistance. In: Hedin, P. A. (ed.). Plant resistance to insects Acs. Symposium Ser 208. Maple Press, Washington: 69-100.
  • Sultana S, Akhtar N, Asif HM (2013) Phytochemical screening and antipyretic effects of hydro-methanol extract of Melia azedarach leaves in rabbits. Bangladesh Journal of Pharmacology 8(2): 214-217.
  • Townsend CC, Guest E (1974) With the collaboration of the Botany Directorate of ministry of Agriculture and Agrarian Reform, Baghdad. Flora of Iraq 3: 477-478.
  • Tyler VE, Brady LR, Robbers JE (1988) Pharmacognosy. 9th edit. Lea and Fabiger, Philadelphia.

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