Serological prevalence of hepatitis viruses in blood samples obtained from donors in blood bank of Al-Diwaniyah Teaching Hospital: Case control study
  • Article Type: Research Article
  • Eurasian Journal of Biosciences, 2020 - Volume 14 Issue 1, pp. 1905-1908
  • Published Online: 30 Jun 2020
  • Open Access Full Text (PDF)

Abstract

The aim of the current study was to estimate the prevalence of various forms of viral hepatitis in blood samples obtained from blood donors at the blood bank of Al-Diwaniyah teaching hospital in the mid-Euphrates region of Iraq. The current case control study was carried out in the blood bank of Al-Diwaniyah teaching hospital at Al-Diwaniyah province, Iraq. The study started on January the 3rd 2019 and ended on February the 15th 2020. During this period we were able to identify 30 samples of blood which were positive for one or more of the known hepatitis viruses. Samples were obtained from donors when they visit the bank for propose of blood donation. Positive results were then collected and data of those positive cases such as age, gender, residency, level of education and socioeconomic status were obtained from the provided cases sheets. In addition, 30 negative records were included to serve as a control group. The most frequent virus was HBV which was detected in 28 out 35 cases (80.0 %) followed by HAV which was detected in 3 patients only (8.6 %). Hepatitis C virus was seen in 2 cases (5.7 %), HEV was detected in a single case and HGV was also detected in a single case.

References

  • Abdullah SM (2018) Prevalence of Hepatitis B and C virus infection and their co-relation with hematological and hepatic parameters in subjects undergoing Premarital Screening in the Jazan Region, Kingdom of Saudi Arabia. Pak J Med Sci 34(2):316-321. https://doi.org/10.12669/pjms.342.14278
  • Alzahrani FM, Muzaheed, Shaikh SS, Alomar AI, Acharya S, Elhadi N (2019) Prevalence of Hepatitis B Virus (HBV) Among Blood Donors in Eastern Saudi Arabia: Results From a Five-Year Retrospective Study of HBV Seromarkers. Ann Lab Med 39(1):81-85.
  • Aydin S (2020) The Effects of Ownership Structure on Time Spend by Physicians with Patients. European Journal of Environment and Public Health, 4(1): em0037. https://doi.org/10.29333/ejeph/6292
  • Badrawy H, Bakry R (2013) Anti-HBc and HBV-DNA detection in blood donors negative for hepatitis B virus surface antigen. Am J Mol Biol ;3:62-66.
  • Behzad-Behbahani A, Mafi-Nejad A, Tabei SZ, Lankarani KB, Torab A, Moaddeb A (2006) Anti-HBc and HBV-DNA detection in blood donors negative for hepatitis B virus surface antigen in reducing risk of transfusion associated HBV infection. Indian J Med Res ;123:37-42.
  • El Beltagy KE, Al Balawi IA, Almuneef M, Memish ZA (2008) Prevalence of hepatitis B virus markers among blood donors in a tertiary hospital in Tabuk, Northwestern Saudi Arabia. Int J Infect Dis ;12:495-499.
  • Habibzadeh F (2014) Viral hepatitis in the Middle East. Lancet 384
  • Igbokwe GO, Zubairu YG, Bello AG (2016) Application of Agroforestry Techniques in the Management of Bamboo. International Journal of Sustainable Agricultural Research, 3(1): 29-34. https://doi.org/10.18488/journal.70/2016.3.1/70.1.29.34
  • Japhet MO, Adesina OA, Donbraye E, Adewumi MO (2011) Hepatitis B core IgM antibody (anti-HBcIgM) among hepatitis B surface antigen (HBsAg) negative blood donors in Nigeria. Virol J 8:513.
  • Kaishima T, Akita T, Ohisa M, Sakamune K, Kurisu A, Sugiyama A, et al. (2018) Cost-effectiveness analyses of anti-hepatitis C virus treatments using quality of life scoring among patients with chronic liver disease in Hiroshima prefecture, Japan. Hepatol Res 48(7):509-20.
  • Kaminski G, Alnaqdy A, Al-Belushi I, Nograles J, Al-Dhahry SH (2006) Evidence of occult hepatitis B virus infection among Omani blood donors: a preliminary study. Med Princ Pract ;15:368-372.
  • Karahasanoğlu FB, Asan A, Sacar S, Turgut H (2013) Costs of treatment, follow-up, and complications of chronic hepatitis B and hepatitis C infections. Balkan Med J 30(4):375-381.
  • Karimi G, Zadsar M, Vafaei N, Sharifi Z, FalahTafti M (2016) Prevalence of antibody to hepatitis B core antigen and hepatitis B virus DNA in HBsAg negative healthy blood donors. Virol J ;13:36. https://doi.org/10.1186/s12985-016-0492-8
  • Kurdi M, Abughararah M, Mulike M, Yamani O, Bugdady M, Noor M (2014) Molecular detection of hepatitis B virus (HBV) among voluntary ELISA positive blood donors in Almadinah Almunawwarah. J Taibah Univ Med Sci 9:166-170.
  • Li HC, Lo SY (2015) Hepatitis C virus: Virology, diagnosis and treatment. World J Hepatol 7(10):1377-1389.
  • Lin KY, Chen GJ, Lee YL, et al. (2017) Hepatitis A virus infection and hepatitis A vaccination in human immunodeficiency virus-positive patients: A review. World J Gastroenterol 23(20):3589-3606. https://doi.org/10.3748/wjg.v23.i20.3589
  • Lok AS, McMahon BJ (2001) Practice Guidelines Committee, American Association for the Study of Liver Diseases. Chronic hepatitis B. Hepatology 34:1225-1241.
  • Mahaba HM, El-Tayeb Ael K, El-Sekibi DK, El Gofaei AF, El-Baz HS, Ismail NA (1997) Pattern of HBsAg positivity in selected groups at King Khalid General Hospital-Hail region, Kingdom of Saudi Arabia. J Family Community Med ;4:30-36.
  • Mahoney FJ, Woodruff BA, Erben JJ, Coleman PJ, Reid EC, Schatz GC, et al. (1993) Effect of a hepatitis B vaccination program on the prevalence of hepatitis B virus infection. J Infect Dis ;167:203-207.
  • Mohammed Abdullah S (2013) Prevalence of hepatitis B and C in donated blood from the Jazan region of Saudi Arabia. Malays J Med Sci ;20:41-46.
  • O’Lawrence H (2019) Lack of Insurance Coverage Affect Access to Healthcare. European Journal of Environment and Public Health, 3(1): em0021. https://doi.org/10.20897/ejeph/3945
  • Pondé RAA (2017) The serological markers of acute infection with hepatitis A, B, C, D, E and G viruses revisited. Arch Virol 162:3587-3602.
  • Ramia S, Ramlawi F, Kanaan M, Klayme S, Naman R (2005) Frequency and significance of antibodies against hepatitis B core (anti-HBc) antigen as the only serological marker for hepatitis B infection in Lebanese blood donors. Epidemiol Infect ;133:695-699.
  • Rizzetto M (2015) Hepatitis D Virus: Introduction and Epidemiology. Cold Spring Harb Perspect Med 5(7):a021576.
  • Sekiba K, Otsuka M, Ohno M, et al. (2018) Hepatitis B virus pathogenesis: Fresh insights into hepatitis B virus RNA. World J Gastroenterol 24(21):2261-2268. https://doi.org/10.3748/wjg.v24.i21.2261
  • Song Y, Bian Y, Petzold M, Ung CO (2014) Prevalence and trend of major transfusion-transmissible infections among blood donors in Western China, 2005 through 2010. Plos One 9:e94528.
  • Udompap P, Kim D, Kim WR. Current and future burden of chronic nonmalignant liver disease. Clin Gastroenterol Hepatol. 2015;13(12):2031-2041. https://doi.org/10.1016/j.cgh.2015.08.015
  • Wang T, Chen J, Zhang Q, et al. (2019) Prevalence of hepatitis G virus infection among 67,348 blood donors in mainland China. BMC Public Health 19(1):685.
  • Webb GW, Dalton HR (2019) Hepatitis E: an underestimated emerging threat. Ther Adv Infect Dis 6:2049936119837162. https://doi.org/10.1177/2049936119837162
  • Weber B, Melchior W, Gehrke R, Doerr HW, Berger A, Rabenau H (2001) Hepatitis B virus markers in anti-HBc only positive individuals. J Med Virol 64:312-319.

License

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.