Seborrheic dermatitis is a recurrent skin disease with a predilection in areas having many sebaceous glands. The etiology of seborrheic dermatitis is still unknown. Several factors are involved in its etiopathogenesis, such as Malassezia, activity of sebaceous disorders, and individualized education. The diagnosis of seborrheic dermatitis is based on the clinical morphology of the scales and erythema, which is typical in sebum-rich areas. If necessary, the diagnosis requires histopathological examination and species identification through culture or polymerase chain reaction. The goal of the management of seborrheic dermatitis is to release and eliminate scales and crust, change fungal colonization, control infections, and regulate erythema and itching. Therapies, such as topical antifungals and corticosteroids, can be given. This literature presents a case of a baby diagnosed with seborrheic dermatitis established through history, physical examination, and Polymerase chain reaction (PCR) to identify the causative microorganism. The results of the examination carried out showed the involvement of Malassezia furfur and Malassezia restricta. We then provided topical corticosteroid and antifungal treatments which led to repair of the lesion within 2 weeks.

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