Religious coping associated with serum cortisol and anxiety symptoms on late-stage breast cancer patients

Abstract

Background: Breast cancer diagnosis is considered meaningful stressor and often accompanied by anxiety. Cortisol correlates with anxiety and can predict breast cancer progressivity. This study aimed to analyze the correlation between religious coping with serum cortisol levels and anxiety symptoms on late-stage of breast cancer patients at Dr. Soetomo Hospital, Surabaya.
Methods: This was a cross-sectional observational analytic study. We used Brief RCOPE to assess patients’ religious coping, Beck Anxiety Inventory (BAI) to measure the symptoms of anxiety, and chemiluminescence method to measure serum cortisol in the morning.
Results: Among 32 subjects, the mean RCOPE positive, RCOPE negative, serum cortisol levels and BAI were 23.25, 12.375, 22.7734, and 12.5313, respectively. Significant correlations were found between negative religious coping and serum cortisol (p = 0.015; r = 0.425), also between negative religious coping and anxiety (p = 0,001; r = 0555). No correlation was found between positive religious coping and serum cortisol, nor between positive religious coping and anxiety.
Conclusion: Higher negative religious coping correlates with higher serum cortisol and higher anxiety.

References

  • Agusmita A, Effendy E, (2019) An anxiety case report with murotal alqur’an approach in woman who got hemodialysis in universitas sumatera utara hospital, Medan. Open Access Macedonian Journal of Medical Sciences 7(16): 2695-2697. https://doi.org/10.3889/oamjms.2019.420
  • Andersen BL, Farrar WB, (2001) Breast Disorders and Breast Cancer. In: Stotland, N. L. and Stewart, D. E. (eds.) Psychological Aspects of Women ‘ s Health Care. Washington, DC: American Psychiatric Press.
  • Bustan MN, Coker AL, Addy CL, Macera CA, Greene F, Sampoerno D, (1993) Oral contraceptive use and breast cancer in Indonesia. Contraception 47(3): 241-249. https://doi.org/10.1016/0010-7824(93)90041-5
  • Catherine C, Camellia V, Husada MS, Loebis B, Effendy E, Amin MM, (2019) Affective psychopathology towards the quality of life of breast cancer patients with radiotherapy in medan, Indonesia. Open Access Macedonian Journal of Medical Sciences 7(9): 1456-1460. https://doi.org/10.3889/oamjms.2019.313
  • Gall TL, Kristjansson E, Charbonneau C, Florack P, (2009) A longitudinal study on the role of spirituality in response to the diagnosis and treatment of breast cancer. Journal of behavioral medicine 32(2): 174-86. https://doi.org/10.1007/s10865-008-9182-3
  • Gaston-johansson F, Haisfield-wolfe ME, Reddick B, Goldstein N, Lawal TA, (2013) The Relationships Among Coping Strategies, Religious Coping, and Spirituality in African American Women With Breast Cancer Receiving Chemotherapy. Oncology Nursing Forum 40(2): 120-131.
  • Hebert R, Zdaniuk B, Schulz R, Scheier M, (2009) Positive and Negative Religious Coping and Well-Being. Journal of Palliative Medicine 12(6): 537-545.
  • İnci A, Açıkgöz Ö, Kalaycı MU, Ülker V (2018) The Positivity Ratios of HBsAg, Anti-HBs and Isolated Anti-HBc in Patients with Breast and Gynecologic Cancers Prior to Chemotherapy. Journal of Clinical and Experimental Investigations, 9(2): 91-94. https://doi.org/10.5799/jcei.433817
  • Ironson G, Solomon GF, Balbin EG, O’Cleirigh C, George A, Kumar M, Larson D, Woods TE, (2002) The Ironson - Woods Spirituality / Religiousness Index Is Associated With Long Survival, Health Behaviors, Less Distress, and Low Cortisol in People With HIV / AIDS. The Society of Behavioral Medicine 24(1): 34-48.
  • Jafarzadeh M, Mousavizadeh K, Joghataei MT, Hashemi Bahremani M, Safa M, Asghari SM (2018).Fibroblast Growth Factor Antagonist Peptide Inhibits Breast Cancer in BALB/c Mice, 13(1): 348-354.
  • Mursyidah NI, Ashariati A, Kusumastuti EH, (2019) Comparison of Breast Cancer 3-years Survival Rate Based on the Pathological Stages. JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga 10(1): 38-43.
  • Pandey M, Thomas BC, Sreerekha P, Ramdas K, Ratheesan K, Parameswaran S, Mathew BS, Rajan B (2005) Quality of Life determinants in women with breast cancer undergoing treatment with curative intent. World Journal of Surgical Oncology 3(63): 1-7.
  • Rosnani R (2017) Coping Mechanism of Career Women with Breast Cancer. Jurnal Ners 12(1): 81-87.
  • Sari DK, Dewi R, Daulay W (2019) Association between family support, coping strategies and anxiety in cancer patients undergoing chemotherapy at General Hospital in Medan, North Sumatera, Indonesia. Asian Pacific Journal of Cancer Prevention 20(10): 3015-3019. https://doi.org/10.31557/APJCP.2019.20.10.3015
  • Sarmila, Noor NN, Suriah (2018) Survival of breast cancer patients in several hospitals of Makassar City 2012-2016. In: ICHSM ‘18: Proceedings of the International Conference on Healthcare Service Management. Faculty of Public Health, Hasanuddin University, Jl. Perintis Kemerdekaan Km. 10, Tamalanrea Indah, Tamalanrea, Tamalanrea Indah, Tamalanrea, 90245, Indonesia: Association for Computing Machinery https://doi.org/10.1145/3242789.3242823
  • Schreiber JA, Brockopp DY (2012) Twenty-five years later--what do we know about religion/spirituality and psychological well-being among breast cancer survivors? A systematic review. Journal of cancer survivorship : research and practice 6(1): 82-94. https://doi.org/10.1007/s11764-011-0193-7
  • Tarakeshwar N, Vanderwerker LC, Paulk E, Pearce MJ, Kasl SV, Prigerson HG (2006) Religious Coping is Associated with the Quality of Life of Patients with Advanced Cancer. Journal of Palliative Medicine 9(3): 646-657.
  • Thuné-boyle IC V, Stygall J, Keshtgar MRS, Davidson TI, Newman SP (2013) Religious / spiritual coping resources and their relationship with adjustment in patients newly diagnosed with breast cancer in the UK. Psycho-Oncology 22: 646-658.
  • Thuné-Boyle IC, Stygall JA, Keshtgar MR, Newman SP (2006) Do religious/spiritual coping strategies affect illness adjustment in patients with cancer? A systematic review of the literature. Social science & medicine (1982) 63(1): 151-64. https://doi.org/10.1016/j.socscimed.2005.11.055
  • Tsiring DA, Evstafeeva EA, Ponomareva IV, Sizova YN (2019) Subject and personal particularities of women having various stages of breast cancer. Electronic Journal of General Medicine, 16(6): em150. https://doi.org/10.29333/ejgm/112266
  • World Health Organization (2014) Cancer Country Profile.
  • Zwingmann C, Muller C, Korber J, Murken S (2008) Religious commitment, religious coping and anxiety: a study in German patients with breast cancer. European Journal of Cancer Care 17(4): 361-370. https://doi.org/10.1111/j.1365-2354.2007.00867.x

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