Ovarian activity improvement and antioxidant effects of Gundelia Microcephala extract in oxidative stress rats
AMA 10th edition
In-text citation: (1), (2), (3), etc.
Reference: Al-kadhi NA, Abass KS, Abbas QS. Ovarian activity improvement and antioxidant effects of Gundelia Microcephala extract in oxidative stress rats. Eurasia J Biosci. 2020;14(1), 747-756.

APA 6th edition
In-text citation: (Al-kadhi et al., 2020)
Reference: Al-kadhi, N. A., Abass, K. S., & Abbas, Q. S. (2020). Ovarian activity improvement and antioxidant effects of Gundelia Microcephala extract in oxidative stress rats. Eurasian Journal of Biosciences, 14(1), 747-756.

In-text citation: (Al-kadhi et al., 2020)
Reference: Al-kadhi, Najdat Ali, Kasim Sakran Abass, and Qays Satwan Abbas. "Ovarian activity improvement and antioxidant effects of Gundelia Microcephala extract in oxidative stress rats". Eurasian Journal of Biosciences 2020 14 no. 1 (2020): 747-756.

In-text citation: (Al-kadhi et al., 2020)
Reference: Al-kadhi, N. A., Abass, K. S., and Abbas, Q. S. (2020). Ovarian activity improvement and antioxidant effects of Gundelia Microcephala extract in oxidative stress rats. Eurasian Journal of Biosciences, 14(1), pp. 747-756.

In-text citation: (Al-kadhi et al., 2020)
Reference: Al-kadhi, Najdat Ali et al. "Ovarian activity improvement and antioxidant effects of Gundelia Microcephala extract in oxidative stress rats". Eurasian Journal of Biosciences, vol. 14, no. 1, 2020, pp. 747-756.

In-text citation: (1), (2), (3), etc.
Reference: Al-kadhi NA, Abass KS, Abbas QS. Ovarian activity improvement and antioxidant effects of Gundelia Microcephala extract in oxidative stress rats. Eurasia J Biosci. 2020;14(1):747-56.


The paper aimed to investigate the antioxidant effects of Gundelia Microcephala extract on some physiological, biochemical parameters and ovarian activities of female rats exposed to oxidative stress. Twenty adult female rats grouped to four groups ( I-IV ) treated with distilled water, Gundelia Microcephala extract, 0.5% H2O2 and Gundelia Microcephala + H2O2 respectively for five weeks. At the end of study the blood collected and centrifuged to obtain serum which kept at deep freeze (-20 °C). Ovaries isolated and preserved in containers contained formalin 10%. Then ovaries were sectioned 5 µm and examined under microscope to observe number and type of follicles with corpus leteum. The results of the study recorded a significant (P<0.05) decrease in the concentration of some hepatic enzymes (GOT and GPT), glucose, lipid fractions (TG and TC), MDA while a significant increase (P<0.05) in concentration of HDL and antioxidant enzymes (glutathione, SOD and catalase) when compared with H2O2 group which recorded a reverse results. However, Gundelia Microcephala + H2O2 group recorded no significant differences (P>0.05) of the studied parameters when compared with the control. Histological results revealed an improvement and enhancement effects on ovarian structure through an acceleration growing of different stages of ovarian follicles and active corpus luteum in Gundelia Microcephala and Gundelia Microcephala + H2O2 groups, while the reverse observations recorded in group treated with H2O2. These alterations companied with the fluctuations of hormonal concentrations in corresponding groups. Finally, concluded the improvement and ameliorating effects of Gundelia Microcephala extract against oxidative stress concerned with hepatoprotective, hypoglycemic, and antioxidant effects enhanced ovarian activity.


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