Microbial study of Trichophyton rubrum isolated from various Tinea infections
  • Article Type: Research Article
  • Eurasian Journal of Biosciences, 2020 - Volume 14 Issue 2, pp. 2553-2558
  • Published Online: 28 Aug 2020
  • Open Access Full Text (PDF)


Dermatophytes infections, especially those affecting the keratinized tissues, are a major concern worldwide and are increasing on a global scale. Dermatophytosis is an infection of the skin, hair, and nails as a result of colonization of the Keratin layers in the body. The factors causing dermatomycosis are classified in three distorted genera, Epidermophyton, Microsporum, and Trichophyton. This study was aimed to isolate and identify Trichiphyton rubrum from different Tinea infection using morphological features including scanning electron microscope examination and to evaluate its sensitivity towards several antifungal drugs. Seventy-three Tinea infections specimens were included in this study. All the clinical specimens were cultured onto sabouraud dextrose agar plates and potato dextrose agar plates and identified using cultural and microscopic features. The positive specimens for Trichiphyton rubrum were tested for susceptibility towards different antifungal drugs. The results showed that from all the clinical specimens (73), included in this study 25 (34.2%) were positive for Trichiphyton rubrum. Tinea corporis was the most common clinical type of Trichiphyton rubrum infection with incidence of 9 (36%). All of the Trichiphyton rubrum isolates were sensitive to Nystatin (NS 100 IU), Amphotericin-B (AP 100 IU) and Itraconazole (IT 10µg), and resistant to Clotrimazole (CC 10µg), Ketoconazole (KT 10µg), and Fluconazole (FLC 10µg). In Conclusion Tinea corporis is the most dermatophytosis caused by Trichiphyton rubrum and Nystatin is the most effective antifungal drug towered it.


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