Influence of palm oil enriched diet on the morpho-functional condition of rat’s mandibular condylar cartilage
AMA 10th edition
In-text citation: (1), (2), (3), etc.
Reference: Krikun EN, Ismailova KR, Luzin VI, Morozov VN, Morozova EN. Influence of palm oil enriched diet on the morpho-functional condition of rat’s mandibular condylar cartilage. Eurasia J Biosci. 2019;13(2), 893-897.

APA 6th edition
In-text citation: (Krikun et al., 2019)
Reference: Krikun, E. N., Ismailova, K. R., Luzin, V. I., Morozov, V. N., & Morozova, E. N. (2019). Influence of palm oil enriched diet on the morpho-functional condition of rat’s mandibular condylar cartilage. Eurasian Journal of Biosciences, 13(2), 893-897.

Chicago
In-text citation: (Krikun et al., 2019)
Reference: Krikun, Evgeniy N., Kamilya R. Ismailova, Vladyslav I. Luzin, Vitaliy N. Morozov, and Elena N. Morozova. "Influence of palm oil enriched diet on the morpho-functional condition of rat’s mandibular condylar cartilage". Eurasian Journal of Biosciences 2019 13 no. 2 (2019): 893-897.

Harvard
In-text citation: (Krikun et al., 2019)
Reference: Krikun, E. N., Ismailova, K. R., Luzin, V. I., Morozov, V. N., and Morozova, E. N. (2019). Influence of palm oil enriched diet on the morpho-functional condition of rat’s mandibular condylar cartilage. Eurasian Journal of Biosciences, 13(2), pp. 893-897.

MLA
In-text citation: (Krikun et al., 2019)
Reference: Krikun, Evgeniy N. et al. "Influence of palm oil enriched diet on the morpho-functional condition of rat’s mandibular condylar cartilage". Eurasian Journal of Biosciences, vol. 13, no. 2, 2019, pp. 893-897.

Vancouver
In-text citation: (1), (2), (3), etc.
Reference: Krikun EN, Ismailova KR, Luzin VI, Morozov VN, Morozova EN. Influence of palm oil enriched diet on the morpho-functional condition of rat’s mandibular condylar cartilage. Eurasia J Biosci. 2019;13(2):893-7.

Abstract

Currently, it is known that saturated fatty acids in palm oil have a negative effect on the body: they activate the thrombus formation process, increase blood cholesterol levels and develop other metabolic disorders, which leads to the development of cardiovascular and oncological diseases, and also to dysfunction of the organs of the gastrointestinal tract. The aim of the study was to establish the morpho-functional condition of mandibular condylar cartilage in white rats of different ages under conditions of excessive use of palm oil and to assess the possibility of correcting the identified changes using the Garcinia Cambogia extract. The study was conducted on 216 white rats of three age groups: immature, mature and senile, divided into 3 groups. 1st group - control; 2nd group - animals treated with palm oil at the rate of 30 g / day / kg; Group 3 - rats, which after 6 weeks of administering palm oil began to receive Garcinia Cambogia extract at a rate of 0.25 g / kg body weight. The periods of observation were 1, 10, 30 and 60 days after the end of 6 weeks from the start of palm oil use. The histologic slides of mandibular condylar cartilage were made according to standard methods. The total width of the condylar cartilage of the lower jaw, the width of its individual zones, the volume content of primary spongiosa, and the number of cells in the zone of subchondral osteogenesis were measured on the sections obtained. The use of palm oil for 6 weeks at the rate of 30 g / day / kg is accompanied by inhibition of the osteogenic function of the condylar cartilage of the lower jaw of experimental animals, which increases with the duration of addition of palm oil to the diet. On day 1 of observation, the maximum in amplitude deviations are observed in immature animals, the minimum - in senile animals. In the future, the rate of increase of changes are maximum in senile animals. The introduction of the Garcinia Cambogia extract at the rate of 0.25 mg / day / kg starting from the 7th week of using palm oil is accompanied by smoothing the negative influence of the experimental conditions on the osteogenic function of the condylar cartilage from 10 to 60 days of observation in immature and mature rats and from 30 to 60 days in senile rats.

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