Extraction of (3-Methyl-2-buten-1-yl β-D-glucopyranoside) of the fruit of plant Capparis spinosa and study effect on breast cancer cells
Amjed Abbawe Salih 1 * , Hussein Abood Idham 2, Nuhad Khaleel Ismaeel 1 3
1 The College of Education for Pure Sciences at the University of Kirkuk, IRAQ2 Directorate General of Education Kirkuk, IRAQ3 The College of Sciences at the University of Diyala, IRAQ
* Corresponding Author
  • Article Type: Research Article
  • Eurasian Journal of Biosciences, 2020 - Volume 14 Issue 2, pp. 4471-4474
  • Published Online: 26 Oct 2020
  • Open Access Full Text (PDF)

Abstract

Caper plant (Cappers Spinoza) separate have been related with diverse biological activities inclusive anti-cancer properties, In this research, researcher used as a treatment for cancer we observe measurements of significant decrease in the level of breast cancer cells at ≥ 0.05,and identify the compound extract (3-Methyl-2-buten-1-yl β-D-glucopyranoside) by spectrum methods (IR,1H.nmr and 13C.nmr) spectroscopy.

Keywords

Caper (Cappers Spinoza) pyran derivatives anti-cancer activity

References

  • Al-Snafi A.E, Yaseen N.Y & Al-Shatry M.M (2015). Anticancer effects of sodium valproate. International Journal of Pharm Tech Research 7(2): 291-297.
  • Al-Snafi, A.E. (2015). The Chemical Constituent and Pharmacological effects of Capprris Spinosa, Indian Journal of Pharmaceutical Science & Research 5(2):93-100.
  • Anand P, Kunnumakkara AB, Sundaram C, et al (2008). Cancer is a Preventable Disease that requires Major Lifestyle Changes. Pharm Res. 25:2097-2116.
  • Becker WM, Kleinsmith LJ, Hardin J, Bertoni GP. (2009). The World of the Cell. 7nd ed. San Francisco: Pearson Education, Inc., publishing as Pearson Benjamin Cummings; 757-790.
  • Ferlay, J., Soerjomataram, I., Dikshit, R., Eser, S., Mathers, C., Rebelo, M.,... & Bray, F. (2015). Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. International journal of cancer, 136(5), E359-E386.
  • Ferlay, J., Soerjomataram, I., Dikshit, R., Eser, S., Mathers, C., Rebelo, M.,... & Bray, F. (2015). Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. International journal of cancer, 136(5), E359-E386.
  • Fidelis, G., Louis, H., Tizhe, T., Onoshe, S. (2019). Curcumin and Curcumin-based derivatives as anti-cancer agents: Recent Nano-Synthetic Methodologies and Anti-cancer Therapeutic Mechanisms. Journal of Medicinal and Chemical Sciences, 2, 59-63.
  • Figueroa-Valverde, L., Francisco, D., Marcela, R., Virginia, M., Elizabeth, M., Maria, L., Elodia, G., Eduardo, P., Lenin, H., Alondra, A., Jhair, C. (2019). Design and Synthesis of a Diaza-bicyclo-naphthalen-oxiranyl-methanone Derivative. Theoretical Analysis of Their Interaction with Cytochrome P450-17A1. Chemical Methodologies, 3, 194-210.
  • Howell A, Anderson AS, Clarke RB, et al (2014). Risk determination and prevention of breast cancer. Breast Cancer Res. 16:446.
  • Inocencio, C., Cowan, R.S., Alcaraz, F., Rivera, D., Fay, M.F. (2005). AFLP fingerprinting in Capparis subgenus Capparis related to the commercial sources of capers. Gen. Res. 52, 137–144.
  • Saad B, Azaizeh H, Said O (2008). Arab Herbal Medicines. Bot Med. 16:32.
  • Sarli, S., Ghasemi, N. (2020). Optimization of biosynthesized Zn nanoparticles by poisonous Taxus baccata leaves extract and evaluation of their effect on the bacterias and MCF-7 cancer cells. Eurasian Chemical Communications, 2, 302-318.
  • Sozzi, G.O. (2008). Capparis spinosa, caper bush. In: Janick, J., Paull, R.E. (Eds.), The encyclopedia of fruit and nuts. CABI Publishing, Oxfordshire, United Kingdompp. 227–232
  • Tesoriere, L.; Butera, D.; Gentile, C.; Livrea, M. A (2007). Bioactive components of caper (Capparis spinosa L.) from Sicily and antioxidant effects in a red meat simulated gastric digestion. J. Agric. Food Chem. 55, 8465-8471
  • Tlili N, Khaldi A, Triki S, Munné-Bosch S. (2010). Phenolic compounds and vitamin antioxidants of caper (Capparis spinosa) Plant Foods Hum Nutr. 65:260–265.
  • Tlili, N., Elfalleh, W., Saadaoui, E., Khaldi, A., Triki, S., Nasri, N. (2011). The caper (Capparis L.): Ethnopharmacology, phytochem-ical and pharmacological properties. Fitoterapia82, 93–1010.

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