Evaluation of oxidative stress and growth status in molecular diagnostic patients with entamoeba histolytica
  • Article Type: Research Article
  • Eurasian Journal of Biosciences, 2020 - Volume 14 Issue 2, pp. 2609-2612
  • Published Online: 28 Aug 2020
  • Open Access Full Text (PDF)

Abstract

In the developing world, amoebiasis is a widespread parasitic disease in which Entameoba histolytica is the causative agent for a human. The aim of this study is to evaluate the end products of oxidative stress include; serum levels of malondialdehyde (MDA), and serum levels of total protein carbonyl (POC) in Entameoba histolytica patients. In addition to estimate the growth retardation of children infected with this parasite. In the current study the sera and stool of 37 patients with Entameoba histolytica infection and 37 healthy children in the control group were diagnosed by Molecular detection techniques. Growth status were calculated and oxidative stress were analyzed. The mean age of the patient was 5.16 ± 4.811 years. There were significant lower differences between the mean of z-score for high and mean z-score for weight in patient than that of controls. T-test demonstrated markedly higher MDA levels, and POC levels were spotted in serum of patients as matched to the patients with control group. It is concluded that the Entameoba histolytica infection was associated with significant oxidative stress and growth retardation.

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