Objective: Dental caries is one of the causes of tooth loss, but it could be stopped by boosting the remineralization process. Bioactive glass 45S5, nano-tricalcium phosphate (nano-TCP), and Biodentine are mineralizing materials. This study aims to evaluate dentin remineralization after bioactive glass 45S5, nano-tricalcium phosphate, and Biodentine are applied.
Methods: Twenty-one dentinal disks (1×1×1 mm) were prepared from 21 extracted premolar teeth. SEM, and XRD tests were performed on dentin samples. The disks were kept in the demineralizing solution for five hours, and the aforementioned tests were carried out again. Then, the disks were divided into three groups (n = 7). The disks received bioactive glass 45S5, nano-TCP, or Biodentine and were covered with a photo-curable glass ionomer. The tests were performed again after 21 days.
Results: Bioactive glass 45S5 and nano-TCP remineralized the dentinal disks, but Biodentine could not.
Conclusion: Bioactive glass and nano-TCP are potentially promising materials for remineralization of tooth structure. It may aid in remineralizing the adjacent demineralized dentin, thus preventing further destruction of the tooth.


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