Environmental pollution and congenital heart defects in Baku
  • Article Type: Research Article
  • Eurasian Journal of Biosciences, 2020 - Volume 14 Issue 1, pp. 1345-1351
  • Published Online: 12 Jun 2020
  • Open Access Full Text (PDF)


The aim is to assess the relationship between congenital heart disease (CHD) and air pollution in Baku in the period 2001-2006. The basis of the research formed the results of the analysis of the information collected on cases of CHD in various hospitals of Baku in the period 2001-2006 and used data from the Azerbaijan ecologists, presented in the social network. In total, there were 633 cases of CHD in Baku over the period examined, which is 28.09% of the total number of newborns with CDF. On average, for the period under study, the absolute increase in CHD was 44.5%, and the growth rate was 138.3%.
 In the period 2001-2006 in Baku, a strong correlation was found between the frequency of the CHF and the average annual concentration of sulfur dioxide in the atmosphere (r = 0.972, p <0.001), formaldehyde (CH2O) - r = 0.706 (p <0.001), nitrogen dioxide (NO2) - r = 0.701 (p<0.001). The average correlation was found between the frequency of CHD and the average annual concentration of sulfuric acid and hydrogen fluoride - r = 0.658 (p <0.05), respectively, as well as the average annual concentration in the furfural atmosphere - r = 0.636 (p <0.05). A good prognostic model of CHD and sulfur dioxide (R2 = 0.945), acceptable models of CHD and formaldehyde (R2 = 0.498), nitrogen dioxide (R2 = 0.491) were obtained.
Possible mechanisms of teratogenicity of air pollutants can be manifested through the cardiovascular system. These mechanisms provide a biological basis for assessing the relationship between exposure to air pollution and congenital heart disease. The results extend the evidence for the Association between air pollution during pregnancy and CHD in the child.


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