Comparison of pre and post-external beam radiation therapy image between squamous cell carcinoma and adenocarcinoma of patients with cervical cancer stage IIIB by measuring primary tumor size in pelvis CT scan without contrast
  • Article Type: Research Article
  • Eurasian Journal of Biosciences, 2020 - Volume 14 Issue 2, pp. 3315-3319
  • Published Online: 21 Sep 2020
  • Open Access Full Text (PDF)

Abstract

Background: Cervical cancer is a gynecologic malignancy which is considered the most frequent cause of death among women. The management for advanced stage is through radiotherapy which consists of External Beam Radiation Therapy (EBRT) and brachytherapy.
The purpose of this study is to compare pre and post External Beam Radiation Therapy (EBRT) image between Squamous Cell Carcinoma and Adenocarcinoma of patients with cervical cancer stage IIIB by measuring primary tumor size in pelvis CT scan without contrast.
Method: This study was conducted in outpatient unit of Radiotherapy Installation Dr. Soetomo General Hospital Surabaya in the period of January 2010 to December 2013.There were 30 patients with cervical cancer stage IIIB. 15 of them have Squamous Cell Carcinoma histopathology result, while the other 15 have Adenocarcinoma histopathology result. The data were secondary data collected from medical records and pelvis CT scan.
Result: Mean of pre-EBRT, post EBRT tumor measurement and post-EBRT tumor size reduction for Squamous Cell Carcinoma and Adenocarcinoma of patients with cervical cancer stage IIIB using pelvis CT scan without contrast are, respectively, 6:01± 1:12 cm and 5:39 ± 1:03 cm, 3.72 ± 0.86 cm and 3.31 ± 0.17 cm, 2:29 ± 0:46 cm (38.42 ± 6.12 %) and 2:06 ± 0:51 cm (38.30 ± 5:19 %).
Conclusion: No evident difference is found in tumor size reduction between Squamous Cell Carcinoma and Adenocarcinoma of patients with cervical cancer stadium IIIB in post-EBRT pelvis CT scan without contrast.

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