Chromosomal analysis of types cleft lip and palate in the City of Kut
  • Article Type: Research Article
  • Eurasian Journal of Biosciences, 2020 - Volume 14 Issue 1, pp. 2007-2010
  • Published Online: 30 Jun 2020
  • Open Access Full Text (PDF)

Abstract

Background: To determine the most chromosomal changes seen in cleft lip and palate in the city of Kut.
Materials and Methods: Chromosomal was studied for all patients. Cases were collected from Al Zahraa Teaching Hospital. The study included analysis of chromosomes of children with cleft lip and their types and knowledge of their causes by diagnosing changes in chromosomes and family history of the condition. The importance of the disease lies in an increase in such cases in recent times. The study was conducted on 60 children between 2018 and 2019 in the city of Kut. Cases were divided into 4 groups: cleft lip (CL), cleft palate (CP only), cleft lip and palate (CLP), cleft lip and palate, and syndrome (any other abnormalities). Chromosomes were analyzed for all cases
Result: The research included 42 male and 18 female cases. The first group CLP included about 42 cases, i.e. (70%), while the second group was 5 cases of CL type(8.3%), and the third case of type CP one case(1.7%) and CLP syndrome 12 cases of ratios were (20 %). And the results of chromosome analysis were for CLP cases, and for the syndrome showed only five cases was chromosome change, that is, there were additional copies present in both chromosome 13 and 18, and normal were found in the karyotype analysis in CL and CP. That is, it is negative for a chromosome defects.

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