Change of immunological blood indicators during follicular cattle mange


The most important problem for veterinarians is cattle skin diseases. This is explained by the fact that various predisposing factors of metabolic disorders and hormonal homeostasis, immunodeficiency states, ecto- and endoparasites play a significant role in the pathogenesis pathology. Follicular cattle mange is one of primary ectoparasite causing skin diseases in the Northern Trans-Urals. Demodectic invasion in cattle proceeds with a manifestation of a multifactorial immune response, which includes: firstly, the impact on the causative agent of invasion of humoral antibodies, and secondly, the development of an allergic reaction of an immediate and delayed type. Immunological studies found that infestation with Demodex bovis tick in the body, a decrease in immunoglobulin A (IgA) is observed in animals by 38.5% with slight damage, by 45.6% with medium damage, and by 54.3% with severe damage. Moreover, the concentration of immunoglobulin M (IgM) is lower in slightly damaged animals by 12.5%, medium damage - by 32.1%, and severe damage - by 39.3% in relation to clinically healthy animals (62.4±0.12 g/l), and the content of immunoglobin G (IgG) is higher by 48.03%, by 93.9%, and by 2.4%, respectively, against 4.83±0.01 g/l, which is explained by their participation in the formation of circulating immune complexes (CIC). The identification of immunological disorders in a macroorganism provides a more complete picture of changes in the animal organism, which in turn is important not only for understanding pathogenesis, but also for developing specific treatment methods.


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