Biochemical and hormonal study in women infected with Toxoplasma gondii


Toxoplasmosis is one of the causative agents of miscarriage or birth defects in pregnant women. This study aimed to assess liver function in women with toxoplasmosis who experience repeated miscarriages. Common biochemical markers were measured to extrapolate the effects of toxoplasmosis on liver function. In total, 37 women were diagnosed with Toxoplasma gondii by ELISA and another 20 uninfected women were selected as a control group. The results demonstrated a dramatic increase in the serum levels of ALT and IgG in patients compared with the control group. In addition, a Pearson’s Coefficient Correlation test revealed positive correlations between ALT and ALK, LH and FSH (at p < 0.01 for both) and patient age and LH (p < 0.05). Preliminary tests indicate that LH and FSH levels are lower in infected groups, but statistical significance was not established. Nevertheless, the current study clearly demonstrates that liver function is affected in patients with Toxoplasma gondii parasites.


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