Association between cervical cancer tumor size based on diffusion-weighted magnetic resonance imaging sequence and surgery results
  • Article Type: Research Article
  • Eurasian Journal of Biosciences, 2020 - Volume 14 Issue 2, pp. 3331-3336
  • Published Online: 21 Sep 2020
  • Open Access Full Text (PDF)


Background: A malignant tumor generally has a large nuclei and exhibits high cell density. Cervical cancer tumor size is a prognostic factor of therapy. Magnetic resonance imagining (MRI) is one of widely used imaging modalities to evaluate primary tumor size and volume. Diffusion-weighted magnetic resonance imaging (DW-MRI) sequence is an MRI technique without contrast material that describes tumor size. Objectives: The research aimed to investigate correlation between cervical cancer tumor size based on DW-MRI sequence and surgery results. Methods: The research was a retrospective cohort study with 8 selected subjects. All The data were taken from cervical cancer stage IIB patients’ medical records from June 2014-February 2015. Tumor volume obtained from MRI examination and surgery results were collected using ellipse formula, followed by statistical test. All data were processed using Pearson’s correlation test. Results: The average longest diameter obtained to DW-MRI was 2.98±1.26 cm and volume was 11.0883±12.873 cm3. The average longest diameter obtained to surgery results was 2.66±1.53 cm and volume was 8.0581±13.378 cm3. The correlation between tumor size obtained with DW-MRI and surgery results based on the longest diameter and volume was r = 0.788, p = 0.02 and r = 0.746, p = 0.03, respectively. Conclusion: We found a strong correlation between tumor size obtained to DW-MRI and surgery results based on the longest diameter, while there was a weak correlation based on the tumor volume.


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